1-Benzothiophene 2-carboxylic acid chloride

1-Benzothiophene 2-carboxylic acid chloride - Names and Identifiers

Name	Benzo[b]thiophene-2-carbonyl chloride
Synonyms	Thianaphthene-2-carbonyl chloride 1-Benzothiophene-2-carbonyl chloride 1-benzothiophene-2-carbonyl chloride BENZO[B]THIOPHENE-2-CARBONYL CHLORIDE Benzo[b]thiophene-2-carbonyl chloride 1-Benzothiophene 2-carboxylic acid chloride Benzo[b]thiophene-2-carboxylic acid chloride 2-(Chlorocarbonyl)-1-benzothiophene, 1-Benzothiophene-2-carbonyl chloride
CAS	39827-11-7
EINECS	679-311-4
InChI	InChI=1/C9H5ClOS/c10-9(11)8-5-6-3-1-2-4-7(6)12-8/h1-5H

1-Benzothiophene 2-carboxylic acid chloride - Physico-chemical Properties

Molecular Formula	C9H5ClOS
Molar Mass	196.65
Density	1.410±0.06 g/cm3(Predicted)
Melting Point	85-86°C
Boling Point	176°C/17mmHg(lit.)
Flash Point	141°C
Vapor Presure	0.000636mmHg at 25°C
Appearance	powder to crystal
Color	White to Orange to Green
BRN	125174
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Sensitive	Moisture Sensitive
Refractive Index	1.68
MDL	MFCD00051635

1-Benzothiophene 2-carboxylic acid chloride - Risk and Safety

Risk Codes	R34 - Causes burns R36 - Irritating to the eyes
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
UN IDs	3261
Hazard Note	Corrosive
Hazard Class	8
Packing Group	III

1-Benzothiophene 2-carboxylic acid chloride - Introduction

Benzo [B] thiophene-2-carbonyl chloride is an organic compound whose chemical formula is C9H5ClOS. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: Benzo [B] thiophene-2-carbonyl chloride is a colorless to pale yellow liquid.
-Melting point: about 30-34 degrees Celsius.
-Boiling point: about 205-209 degrees Celsius.
-Density: about 1.36 g/mL.
-Solubility: Soluble in organic solvents, such as methanol and dichloromethane.

Use:
Benzo [B] thiophene-2-carbonyl chloride are often used in organic synthesis as important intermediates. It can be used to synthesize biologically active compounds, such as drugs and pesticides; it can also be used to synthesize organic materials such as dyes, coatings and optoelectronic devices.

Preparation Method:
Benzo [B] thiophene-2-carbonyl chloride are generally prepared by reacting p-benzothiophen-2-one (Benzo [B] thiophene-2-one) with thionyl chloride. This reaction is usually carried out under an inert atmosphere, and the product is formed by gradually adding thionyl chloride to the reaction system while heating the reaction to an appropriate temperature and maintaining it for a certain period of time.

Safety Information:
Benzo [B] thiophene-2-carbonyl chloride are irritating and corrosive and should avoid contact with skin, eyes and mucous membranes. Use appropriate protective measures such as chemical protective clothing, goggles and gloves. Keep away from combustibles and heat sources during storage and handling.

Last Update：2024-04-09 02:00:46